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Super enhancers: Pathogenic roles and potential therapeutic targets for acute myeloid leukemia (AML)
Acute myeloid leukemia (AML) is a malignant hematological tumor with disordered oncogenes/tumor suppressor genes and limited treatments. The potent anti-cancer effects of bromodomain and extra-terminal domain (BET) inhibitors, targeting the key component of super enhancers, in early clinical trials...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485276/ https://www.ncbi.nlm.nih.gov/pubmed/36157504 http://dx.doi.org/10.1016/j.gendis.2022.01.006 |