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Super enhancers: Pathogenic roles and potential therapeutic targets for acute myeloid leukemia (AML)

Acute myeloid leukemia (AML) is a malignant hematological tumor with disordered oncogenes/tumor suppressor genes and limited treatments. The potent anti-cancer effects of bromodomain and extra-terminal domain (BET) inhibitors, targeting the key component of super enhancers, in early clinical trials...

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Detalles Bibliográficos
Autores principales: Cao, Ziyang, Shu, Yi, Wang, Jinxia, Wang, Chunxia, Feng, Tienan, Yang, Li, Shao, Jingbo, Zou, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485276/
https://www.ncbi.nlm.nih.gov/pubmed/36157504
http://dx.doi.org/10.1016/j.gendis.2022.01.006