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Long noncoding RNA XIST: Mechanisms for X chromosome inactivation, roles in sex-biased diseases, and therapeutic opportunities

Sexual dimorphism has been reported in various human diseases including autoimmune diseases, neurological diseases, pulmonary arterial hypertension, and some types of cancers, although the underlying mechanisms remain poorly understood. The long noncoding RNA (lncRNA) X-inactive specific transcript...

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Detalles Bibliográficos
Autores principales: Li, Jianjian, Ming, Zhe, Yang, Liuyi, Wang, Tingxuan, Liu, Gaowen, Ma, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485286/
https://www.ncbi.nlm.nih.gov/pubmed/36157489
http://dx.doi.org/10.1016/j.gendis.2022.04.007