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Epigenetic modifications and targeted therapy in pediatric acute myeloid leukemia

Acute myeloid leukemia (AML) is a hematological malignancy resulting from the genetic alterations and epigenetic dysregulations of the hematopoietic progenitor cells. One-third of children with AML remain at risk of relapse even though outcomes have improved in recent decades. Epigenetic dysregulati...

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Detalles Bibliográficos
Autores principales: Xu, Huan, Wen, Yuxi, Jin, Runming, Chen, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485478/
https://www.ncbi.nlm.nih.gov/pubmed/36147798
http://dx.doi.org/10.3389/fped.2022.975819