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Endosomal recycling defects link Huntington’s disease with McLeod syndrome

Chhetri and colleagues (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202112073) show that Rab11-mediated endosomal recycling regulates cell surface expression of McLeod syndrome protein XK. Mutant huntingtin interferes with the recycling of XK to the cell surface and significantly reduces mangane...

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Detalles Bibliográficos
Autores principales: Marsan, Elise, Huang, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485561/
https://www.ncbi.nlm.nih.gov/pubmed/36112418
http://dx.doi.org/10.1083/jcb.202208164