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Synaptic determinants of cholinergic interneurons hyperactivity during parkinsonism
Parkinson’s disease is a neurodegenerative ailment generated by the loss of dopamine in the basal ganglia, mainly in the striatum. The disease courses with increased striatal levels of acetylcholine, disrupting the balance among these modulatory transmitters. These modifications disturb the excitato...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485566/ https://www.ncbi.nlm.nih.gov/pubmed/36147730 http://dx.doi.org/10.3389/fnsyn.2022.945816 |