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Synaptic determinants of cholinergic interneurons hyperactivity during parkinsonism

Parkinson’s disease is a neurodegenerative ailment generated by the loss of dopamine in the basal ganglia, mainly in the striatum. The disease courses with increased striatal levels of acetylcholine, disrupting the balance among these modulatory transmitters. These modifications disturb the excitato...

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Detalles Bibliográficos
Autores principales: Padilla-Orozco, Montserrat, Duhne, Mariana, Fuentes-Serrano, Alejandra, Ortega, Aidán, Galarraga, Elvira, Bargas, José, Lara-González, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485566/
https://www.ncbi.nlm.nih.gov/pubmed/36147730
http://dx.doi.org/10.3389/fnsyn.2022.945816