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Development and characterization of a preclinical total marrow irradiation conditioning-based bone marrow transplant model for sickle cell disease

Sickle cell disease (SCD) is a serious global health problem, and currently, the only curative option is hematopoietic stem cell transplant (HCT). However, myeloablative total body irradiation (TBI)-based HCT is associated with high mortality/morbidity in SCD patients. Therefore, reduced-intensity (...

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Detalles Bibliográficos
Autores principales: Sargur Madabushi, Srideshikan, Fouda, Raghda, Ghimire, Hemendra, Abdelhamid, Amr M. H., Lim, Ji Eun, Vishwasrao, Paresh, Kiven, Stacy, Brooks, Jamison, Zuro, Darren, Rosenthal, Joseph, Guha, Chandan, Gupta, Kalpna, Hui, Susanta K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485604/
https://www.ncbi.nlm.nih.gov/pubmed/36147914
http://dx.doi.org/10.3389/fonc.2022.969429