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Development and characterization of a preclinical total marrow irradiation conditioning-based bone marrow transplant model for sickle cell disease
Sickle cell disease (SCD) is a serious global health problem, and currently, the only curative option is hematopoietic stem cell transplant (HCT). However, myeloablative total body irradiation (TBI)-based HCT is associated with high mortality/morbidity in SCD patients. Therefore, reduced-intensity (...
Autores principales: | Sargur Madabushi, Srideshikan, Fouda, Raghda, Ghimire, Hemendra, Abdelhamid, Amr M. H., Lim, Ji Eun, Vishwasrao, Paresh, Kiven, Stacy, Brooks, Jamison, Zuro, Darren, Rosenthal, Joseph, Guha, Chandan, Gupta, Kalpna, Hui, Susanta K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485604/ https://www.ncbi.nlm.nih.gov/pubmed/36147914 http://dx.doi.org/10.3389/fonc.2022.969429 |
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