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Advances in the research of the mechanism of secondary resistance to imatinib in gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. At present, surgery is the first-line treatment for primary resectable GISTs; however, the recurrence rate is high. Imatinib mesylate (IM) is an effective first-line drug used for the treatm...

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Detalles Bibliográficos
Autores principales: Hu, Xiangchen, Wang, Zhe, Su, Peng, Zhang, Qiqi, Kou, Youwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485670/
https://www.ncbi.nlm.nih.gov/pubmed/36147927
http://dx.doi.org/10.3389/fonc.2022.933248