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Effectiveness and mechanism of metformin in animal models of pulmonary fibrosis: A preclinical systematic review and meta-analysis

Background: Pulmonary fibrosis (PF) is a lung disease with no curative drug, characterized by a progressive decrease in lung function. Metformin (MET) is a hypoglycemic agent with the advantages of high safety and low cost and has been used in several in vivo trials to treat fibrotic diseases. Objec...

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Detalles Bibliográficos
Autores principales: Wu, Xuanyu, Xiao, Xiang, Chen, Xinyu, Yang, Maoyi, Hu, Zhipeng, Shuai, Sijia, Fu, Qinwei, Yang, Han, Du, Quanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485720/
https://www.ncbi.nlm.nih.gov/pubmed/36147352
http://dx.doi.org/10.3389/fphar.2022.948101