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Effectiveness and mechanism of metformin in animal models of pulmonary fibrosis: A preclinical systematic review and meta-analysis
Background: Pulmonary fibrosis (PF) is a lung disease with no curative drug, characterized by a progressive decrease in lung function. Metformin (MET) is a hypoglycemic agent with the advantages of high safety and low cost and has been used in several in vivo trials to treat fibrotic diseases. Objec...
Autores principales: | Wu, Xuanyu, Xiao, Xiang, Chen, Xinyu, Yang, Maoyi, Hu, Zhipeng, Shuai, Sijia, Fu, Qinwei, Yang, Han, Du, Quanyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485720/ https://www.ncbi.nlm.nih.gov/pubmed/36147352 http://dx.doi.org/10.3389/fphar.2022.948101 |
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