Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages

Acute liver failure (ALF) is an unfavorable condition characterized by the rapid loss of liver function and high mortality. Chrysophanol-8-O-glucoside (CPOG) is an anthraquinone derivative isolated from rhubarb. This study aims to evaluate the protective effect of CPOG on lipopolysaccharide (LPS)/D-...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tao, Lu, Zhuo, Qu, Xin-Hui, Xiong, Zi-Ying, Wu, Ya-Ting, Luo, Yong, Zhang, Zi-Yu, Han, Xiao-Jian, Xie, Cai-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485814/
https://www.ncbi.nlm.nih.gov/pubmed/36147355
http://dx.doi.org/10.3389/fphar.2022.951521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485814/
https://www.ncbi.nlm.nih.gov/pubmed/36147355
http://dx.doi.org/10.3389/fphar.2022.951521

Ejemplares similares