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Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages

Acute liver failure (ALF) is an unfavorable condition characterized by the rapid loss of liver function and high mortality. Chrysophanol-8-O-glucoside (CPOG) is an anthraquinone derivative isolated from rhubarb. This study aims to evaluate the protective effect of CPOG on lipopolysaccharide (LPS)/D-...

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Detalles Bibliográficos
Autores principales:	Wang, Tao, Lu, Zhuo, Qu, Xin-Hui, Xiong, Zi-Ying, Wu, Ya-Ting, Luo, Yong, Zhang, Zi-Yu, Han, Xiao-Jian, Xie, Cai-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485814/ https://www.ncbi.nlm.nih.gov/pubmed/36147355 http://dx.doi.org/10.3389/fphar.2022.951521

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