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Super-enhancer associated core regulatory circuits mediate susceptibility to retinoic acid in neuroblastoma cells
Neuroblastoma is a pediatric tumour that accounts for more than 15% of cancer-related deaths in children. High-risk tumours are often difficult to treat, and patients’ survival chances are less than 50%. Retinoic acid treatment is part of the maintenance therapy given to neuroblastoma patients; howe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485839/ https://www.ncbi.nlm.nih.gov/pubmed/36147741 http://dx.doi.org/10.3389/fcell.2022.943924 |