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A novel 16-gene alternative mRNA splicing signature predicts tumor relapse and indicates immune activity in stage I–III hepatocellular carcinoma

Background: Hepatocellular carcinoma (HCC) is a lethal disease with high relapse and dismal survival rates. Alternative splicing (AS) plays a crucial role in tumor progression. Herein, we aim to integratedly analyze the relapse-associated AS events and construct a signature predicting tumor relapse...

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Detalles Bibliográficos
Autores principales: Chen, Xu-Xiao, Zhang, Bao-Hua, Lu, Yan-Cen, Li, Zi-Qiang, Chen, Cong-Yan, Yang, Yu-Chen, Chen, Yong-Jun, Ma, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485890/
https://www.ncbi.nlm.nih.gov/pubmed/36147313
http://dx.doi.org/10.3389/fphar.2022.939912