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Induced hepatic stem cells are suitable for human hepatocyte production

Human hepatocytes were transfected with Sendai virus vectors (SeV) expressing OCT3/4, SOX2, KLF4, and C-MYC to produce hepatocyte-derived induced pluripotent stem cells (iPSCs). The messenger RNA (mRNA) expression of undifferentiated markers (passage 19-21) and hepatocyte-specific markers (HSMs) (pa...

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Detalles Bibliográficos
Autores principales: Nakashima, Yoshiki, Miyagi-Shiohira, Chika, Saitoh, Issei, Watanabe, Masami, Matsushita, Masayuki, Tsukahara, Masayoshi, Noguchi, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485912/
https://www.ncbi.nlm.nih.gov/pubmed/36147945
http://dx.doi.org/10.1016/j.isci.2022.105052