Human STING Is Regulated by an Autoinhibitory Mechanism for Type I Interferon Production

Stimulator of interferon genes (STING) plays a pivotal role in type I interferon-mediated innate immune response to the cytoplasmic detection of aberrant DNA. STING is a membrane protein localized in endoplasmic reticulum (ER), which upon stimulation translocates to Golgi apparatus and activates dow...

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Detalles Bibliográficos
Autores principales: Qi, Shishi, Wang, Changwan, Zhang, Rui, Zhu, Junyan, Hou, Xianteng, Jiang, Yingbo, Li, Jiaxin, Ren, Miao, Li, Muwang, Hou, Fajian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485926/
https://www.ncbi.nlm.nih.gov/pubmed/35104824
http://dx.doi.org/10.1159/000521734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485926/
https://www.ncbi.nlm.nih.gov/pubmed/35104824
http://dx.doi.org/10.1159/000521734

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