Comparison of LC-MS/MS and EMIT methods for the precise determination of blood sirolimus in children with vascular anomalies

Sirolimus (SRL) is a mammalian target of rapamycin (mTOR) inhibitor. The whole blood concentration of SRL is routinely monitored to tailor dosage and prevent toxicity. Currently, the enzyme multiplied immunoassay technique (EMIT) is often applied to perform therapeutic drug monitoring (TDM) of SRL,...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yue-Tao, Dai, Hao-Ran, Li, Yue, Zhang, Yuan-Yuan, Guo, Hong-Li, Ding, Xuan-Sheng, Hu, Ya-Hui, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486013/
https://www.ncbi.nlm.nih.gov/pubmed/36147342
http://dx.doi.org/10.3389/fphar.2022.925018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486013/
https://www.ncbi.nlm.nih.gov/pubmed/36147342
http://dx.doi.org/10.3389/fphar.2022.925018

Ejemplares similares