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GLP-1 attenuates intestinal fat absorption and chylomicron production via vagal afferent nerves originating in the portal vein
BACKGROUND/OBJECTIVE: GLP-1R agonists have been shown to reduce fasting and postprandial plasma lipids, both of which are independent risk factors for the development of cardiovascular disease. However, how endogenous GLP-1 – which is rapidly degraded – modulates intestinal and hepatic lipid metabol...
Autores principales: | Hoffman, Simon, Alvares, Danielle, Adeli, Khosrow |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486018/ https://www.ncbi.nlm.nih.gov/pubmed/36067913 http://dx.doi.org/10.1016/j.molmet.2022.101590 |
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