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RNA modification writer expression profiles predict clinical outcomes and guide neoadjuvant immunotherapy in non-small cell lung cancer

BACKGROUND: RNA modifications, including adenosine-to-inosine RNA editing, alternative polyadenylation, m(1)A and m(6)A, play a significant role in tumorigenesis and tumor immunity. However, the functions of RNA modification enzymes (writers) in immunotherapy and tumor microenvironment (TME) remain...

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Detalles Bibliográficos
Autores principales: Zhou, Bolun, Bie, Fenglong, Zang, Ruochuan, Zhang, Moyan, Song, Peng, Liu, Lei, Peng, Yue, Bai, Guangyu, Zhao, Jun, Gao, Shugeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486036/
https://www.ncbi.nlm.nih.gov/pubmed/36116215
http://dx.doi.org/10.1016/j.ebiom.2022.104268