Phase-separation antagonists potently inhibit transcription and broadly increase nucleosome density

Biomolecular condensates are self-organized membraneless bodies involved in many critical cellular activities, including ribosome biogenesis, protein synthesis, and gene transcription. Aliphatic alcohols are commonly used to study biomolecular condensates, but their effects on transcription are uncl...

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Detalles Bibliográficos
Autores principales: Meduri, Rajyalakshmi, Rubio, Linda S., Mohajan, Suman, Gross, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486037/
https://www.ncbi.nlm.nih.gov/pubmed/35963432
http://dx.doi.org/10.1016/j.jbc.2022.102365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486037/
https://www.ncbi.nlm.nih.gov/pubmed/35963432
http://dx.doi.org/10.1016/j.jbc.2022.102365

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