Paeoniflorin directly binds to TNFR1 to regulate podocyte necroptosis in diabetic kidney disease

Necroptosis was elevated in both tubulointerstitial and glomerular renal tissue in patients with diabetic kidney disease (DKD), and was most pronounced on glomerulus in the stage with macroalbuminuria. This study further explored whether paeoniflorin (PF) could affect podocyte necroptosis to protect...

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Detalles Bibliográficos
Autores principales: Wang, Xian, Liu, Xue-qi, Jiang, Ling, Huang, Yue-bo, Zeng, Han-xu, Zhu, Qi-jin, Qi, Xiang-ming, Wu, Yong-gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486100/
https://www.ncbi.nlm.nih.gov/pubmed/36147345
http://dx.doi.org/10.3389/fphar.2022.966645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486100/
https://www.ncbi.nlm.nih.gov/pubmed/36147345
http://dx.doi.org/10.3389/fphar.2022.966645

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