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Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22(phox) by thiol modification

The transmembrane protein p22(phox) heterodimerizes with NADPH oxidase (Nox) 1–4 and is essential for the reactive oxygen species-producing capacity of oxidases. Missense mutations in the p22(phox) gene prevent the formation of phagocytic Nox2-based oxidase, which contributes to host defense. This r...

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Detalles Bibliográficos
Autores principales: Miyano, Kei, Okamoto, Shuichiro, Kajikawa, Mizuho, Kiyohara, Takuya, Kawai, Chikage, Yamauchi, Akira, Kuribayashi, Futoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486109/
https://www.ncbi.nlm.nih.gov/pubmed/36122532
http://dx.doi.org/10.1016/j.redox.2022.102479