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Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22(phox) by thiol modification
The transmembrane protein p22(phox) heterodimerizes with NADPH oxidase (Nox) 1–4 and is essential for the reactive oxygen species-producing capacity of oxidases. Missense mutations in the p22(phox) gene prevent the formation of phagocytic Nox2-based oxidase, which contributes to host defense. This r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486109/ https://www.ncbi.nlm.nih.gov/pubmed/36122532 http://dx.doi.org/10.1016/j.redox.2022.102479 |