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In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide

Dynamic nuclear polarization NMR spectroscopy was used to investigate the effect of the antimicrobial peptide (AMP) maculatin 1.1 on E. coli cells. The enhanced (15)N NMR signals from nucleic acids, proteins and lipids identified a number of unanticipated physiological responses to peptide stress, r...

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Detalles Bibliográficos
Autores principales: Separovic, Frances, Hofferek, Vinzenz, Duff, Anthony P., McConville, Malcom J., Sani, Marc-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486116/
https://www.ncbi.nlm.nih.gov/pubmed/36147732
http://dx.doi.org/10.1016/j.yjsbx.2022.100074