Cargando…

Pyrancoumarin derivative LP4C targeting of pyrimidine de novo synthesis pathway inhibits MRSA biofilm and virulence

Staphylococcus aureus poses a serious public health threat because of its multidrug resistance and biofilm formation ability. Hence, developing novel anti-biofilm agents and finding targets are needed to mitigate the proliferation of drug-resistant pathogens. In our previous study, we showed that th...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yongsheng, Su, Shan, Yu, Moxi, Zhai, Dongshen, Hou, Yachen, Zhao, Hui, Ma, Xue, Jia, Min, Xue, Xiaoyan, Li, Mingkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486200/
https://www.ncbi.nlm.nih.gov/pubmed/36147327
http://dx.doi.org/10.3389/fphar.2022.959736