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Pyrancoumarin derivative LP4C targeting of pyrimidine de novo synthesis pathway inhibits MRSA biofilm and virulence
Staphylococcus aureus poses a serious public health threat because of its multidrug resistance and biofilm formation ability. Hence, developing novel anti-biofilm agents and finding targets are needed to mitigate the proliferation of drug-resistant pathogens. In our previous study, we showed that th...
Autores principales: | Liu, Yongsheng, Su, Shan, Yu, Moxi, Zhai, Dongshen, Hou, Yachen, Zhao, Hui, Ma, Xue, Jia, Min, Xue, Xiaoyan, Li, Mingkai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486200/ https://www.ncbi.nlm.nih.gov/pubmed/36147327 http://dx.doi.org/10.3389/fphar.2022.959736 |
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