Personalized neoantigen vaccine combined with PD-1 blockade increases CD8(+) tissue-resident memory T-cell infiltration in preclinical hepatocellular carcinoma models

BACKGROUND: Personalized neoantigen vaccine could induce a robust antitumor immune response in multiple cancers, whose efficacy could be further enhanced by combining with programmed cell death 1 blockade (α-PD-1). However, the corresponding immune response and synergistic mechanisms remain largely...

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Detalles Bibliográficos
Autores principales: Chen, Hengkai, Li, Zhenli, Qiu, Liman, Dong, Xiuqing, Chen, Geng, Shi, Yingjun, Cai, Linsheng, Liu, Wenhan, Ye, Honghao, Zhou, Yang, Ouyang, Jiahe, Cai, Zhixiong, Liu, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486396/
https://www.ncbi.nlm.nih.gov/pubmed/36113894
http://dx.doi.org/10.1136/jitc-2021-004389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486396/
https://www.ncbi.nlm.nih.gov/pubmed/36113894
http://dx.doi.org/10.1136/jitc-2021-004389

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