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Effects of adjunctive pimavanserin and current antipsychotic treatment on QT interval prolongation in patients with schizophrenia

BACKGROUND: Pimavanserin prolongs the QT interval, with mean increases in corrected QT (QTc) of 5–8 ms, and is currently being investigated for the treatment of negative symptoms of schizophrenia. OBJECTIVES: To assess QT interval prolongation in 3 studies investigating once-daily pimavanserin as an...

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Detalles Bibliográficos
Autores principales: Bugarski-Kirola, Dragana, Nunez, Rene, Odetalla, Ramzey, Liu, I-Yuan, Turner, Mary Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486460/
https://www.ncbi.nlm.nih.gov/pubmed/36147980
http://dx.doi.org/10.3389/fpsyt.2022.892199