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Hyperactivation of the proteasome in Caenorhabditis elegans protects against proteotoxic stress and extends lifespan
Virtually all age-related neurodegenerative diseases (NDs) can be characterized by the accumulation of proteins inside and outside the cell that are thought to significantly contribute to disease pathogenesis. One of the cell’s primary systems for the degradation of misfolded/damaged proteins is the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486566/ https://www.ncbi.nlm.nih.gov/pubmed/36007615 http://dx.doi.org/10.1016/j.jbc.2022.102415 |