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The histone deacetylases Rpd3 and Hst1 antagonistically regulate de novo NAD(+) metabolism in the budding yeast Saccharomyces cerevisiae

NAD(+) is a cellular redox cofactor involved in many essential processes. The regulation of NAD(+) metabolism and the signaling networks reciprocally interacting with NAD(+)-producing metabolic pathways are not yet fully understood. The NAD(+)-dependent histone deacetylase (HDAC) Hst1 has been shown...

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Detalles Bibliográficos
Autores principales: Groth, Benjamin, Huang, Chi-Chun, Lin, Su-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486569/
https://www.ncbi.nlm.nih.gov/pubmed/36007612
http://dx.doi.org/10.1016/j.jbc.2022.102410