Efficient permutation-based genome-wide association studies for normal and skewed phenotypic distributions

MOTIVATION: Genome-wide association studies (GWAS) are an integral tool for studying the architecture of complex genotype and phenotype relationships. Linear mixed models (LMMs) are commonly used to detect associations between genetic markers and a trait of interest, while at the same time allowing...

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Detalles Bibliográficos
Autores principales: John, Maura, Ankenbrand, Markus J, Artmann, Carolin, Freudenthal, Jan A, Korte, Arthur, Grimm, Dominik G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genes Track
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486594/
https://www.ncbi.nlm.nih.gov/pubmed/36124808
http://dx.doi.org/10.1093/bioinformatics/btac455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486594/
https://www.ncbi.nlm.nih.gov/pubmed/36124808
http://dx.doi.org/10.1093/bioinformatics/btac455

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