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Efficient permutation-based genome-wide association studies for normal and skewed phenotypic distributions
MOTIVATION: Genome-wide association studies (GWAS) are an integral tool for studying the architecture of complex genotype and phenotype relationships. Linear mixed models (LMMs) are commonly used to detect associations between genetic markers and a trait of interest, while at the same time allowing...
Autores principales: | John, Maura, Ankenbrand, Markus J, Artmann, Carolin, Freudenthal, Jan A, Korte, Arthur, Grimm, Dominik G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486594/ https://www.ncbi.nlm.nih.gov/pubmed/36124808 http://dx.doi.org/10.1093/bioinformatics/btac455 |
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