Direct capture and sequencing reveal ultra-short single-stranded DNA in biofluids

Cell-free DNA (cfDNA) has become the predominant analyte of liquid biopsy; however, recent studies suggest the presence of subnucleosomal-sized DNA fragments in circulation that are likely single-stranded. Here, we report a method called direct capture and sequencing (DCS) tailored to recover such f...

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Detalles Bibliográficos
Autores principales: Cheng, Lauren Y., Dai, Peng, Wu, Lucia R., Patel, Abhijit A., Zhang, David Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486625/
https://www.ncbi.nlm.nih.gov/pubmed/36147958
http://dx.doi.org/10.1016/j.isci.2022.105046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486625/
https://www.ncbi.nlm.nih.gov/pubmed/36147958
http://dx.doi.org/10.1016/j.isci.2022.105046

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