Localized PD-1 Blockade in a Mouse Model of Renal Cell Carcinoma

Herein we report the impact of localized delivery of an anti-mouse PD-1-specific monoclonal antibody (aPD1) on Renca tumors in the resulting T cell responses and changes in broader immune gene expression profiles. Renca is a BALB/c mice syngeneic tumor that has been used to model human renal cell ca...

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Detalles Bibliográficos
Autores principales: Pham, Ngoc B., Abraham, Nevil, Velankar, Ketki Y., Schueller, Nathan R., Philip, Errol J., Jaber, Yasmeen, Gawalt, Ellen S., Fan, Yong, Pal, Sumanta K., Meng, Wilson S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486680/
https://www.ncbi.nlm.nih.gov/pubmed/36132332
http://dx.doi.org/10.3389/fddev.2022.838458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486680/
https://www.ncbi.nlm.nih.gov/pubmed/36132332
http://dx.doi.org/10.3389/fddev.2022.838458

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