Identification of a Phage Display-Derived Peptide Interacting with the N-Terminal Region of Factor VII Activating Protease (FSAP) Enables Characterization of Zymogen Activation

[Image: see text] Factor VII Activating protease (FSAP) has a protective effect in diverse disease conditions as inferred from studies in FSAP(–/–) mice and humans deficient in FSAP activity due to single-nucleotide polymorphism. The zymogen form of FSAP in plasma is activated by extracellular histo...

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Detalles Bibliográficos
Autores principales: Berge-Seidl, Sebastian, Nielsen, Nis Valentin, Rodriguez Alfonso, Armando A., Etscheid, Michael, Kandanur, Sai Priya Sarma, Haug, Bengt Erik, Stensland, Maria, Thiede, Bernd, Karacan, Merve, Preising, Nico, Wiese, Sebastian, Ständker, Ludger, Declerck, Paul J., Løset, Geir Åge, Kanse, Sandip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486805/
https://www.ncbi.nlm.nih.gov/pubmed/36070465
http://dx.doi.org/10.1021/acschembio.2c00538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486805/
https://www.ncbi.nlm.nih.gov/pubmed/36070465
http://dx.doi.org/10.1021/acschembio.2c00538

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