Cargando…
Identification of a Phage Display-Derived Peptide Interacting with the N-Terminal Region of Factor VII Activating Protease (FSAP) Enables Characterization of Zymogen Activation
[Image: see text] Factor VII Activating protease (FSAP) has a protective effect in diverse disease conditions as inferred from studies in FSAP(–/–) mice and humans deficient in FSAP activity due to single-nucleotide polymorphism. The zymogen form of FSAP in plasma is activated by extracellular histo...
Autores principales: | Berge-Seidl, Sebastian, Nielsen, Nis Valentin, Rodriguez Alfonso, Armando A., Etscheid, Michael, Kandanur, Sai Priya Sarma, Haug, Bengt Erik, Stensland, Maria, Thiede, Bernd, Karacan, Merve, Preising, Nico, Wiese, Sebastian, Ständker, Ludger, Declerck, Paul J., Løset, Geir Åge, Kanse, Sandip M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486805/ https://www.ncbi.nlm.nih.gov/pubmed/36070465 http://dx.doi.org/10.1021/acschembio.2c00538 |
Ejemplares similares
-
Design and Characterization of a New pVII Combinatorial Phage Display Peptide Library for Protease Substrate Mining Using Factor VII Activating Protease (FSAP) as Model
por: Kara, Emrah, et al.
Publicado: (2020) -
Characterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP)
por: Nielsen, Nis V., et al.
Publicado: (2019) -
Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice
por: Artunc, Ferruh, et al.
Publicado: (2021) -
FSAP Protects against Histone-Mediated Increase in Endothelial Permeability In Vitro
por: Cui, Xue Yan, et al.
Publicado: (2022) -
VEGF-A-Cleavage by FSAP and Inhibition of Neo-Vascularization
por: Uslu, Özgür, et al.
Publicado: (2019)