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Proof-Reading Thioesterase Boosts Activity of Engineered Nonribosomal Peptide Synthetase
[Image: see text] Nonribosomal peptide synthetases (NRPSs) are a vast source of valuable natural products, and re-engineering them is an attractive path toward structurally diversified active compounds. NRPS engineering often requires heterologous expression, which is hindered by the enormous size o...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486807/ https://www.ncbi.nlm.nih.gov/pubmed/36044980 http://dx.doi.org/10.1021/acschembio.2c00341 |