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Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region

[Image: see text] Influenza A viruses pose a serious pandemic risk, while generation of efficient vaccines against seasonal variants remains challenging. There is thus a pressing need for new treatment options. We report here a set of macrocyclic peptides that inhibit influenza A virus infection at...

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Detalles Bibliográficos
Autores principales: Pascha, Mirte N., Thijssen, Vito, Egido, Julia E., Linthorst, Mirte W., van Lanen, Jipke H., van Dongen, David A. A., Hopstaken, Antonius J. P., van Kuppeveld, Frank J. M., Snijder, Joost, de Haan, Cornelis A. M., Jongkees, Seino A. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486808/
https://www.ncbi.nlm.nih.gov/pubmed/35926224
http://dx.doi.org/10.1021/acschembio.2c00040