Cargando…

Analysis of the Sequence Preference of Saporin by Deep Sequencing

[Image: see text] Ribosome-inactivating proteins (RIPs) are RNA:adenosine glycosidases that inactivate eukaryotic ribosomes by depurinating the sarcin-ricin loop (SRL) in 28S rRNA. The GAGA sequence at the top of the SRL or at the top of a hairpin loop is assumed to be their target motif. Saporin is...

Descripción completa

Detalles Bibliográficos
Autores principales: Hauf, Samuel, Rotrattanadumrong, Rachapun, Yokobayashi, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486812/
https://www.ncbi.nlm.nih.gov/pubmed/35969718
http://dx.doi.org/10.1021/acschembio.2c00531