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NRF1-mediated microglial activation triggers high-altitude cerebral edema

High-altitude cerebral edema (HACE) is a potentially fatal encephalopathy associated with a time-dependent exposure to the hypobaric hypoxia of altitude. The formation of HACE is affected by both vasogenic and cytotoxic edema. The over-activated microglia potentiate the damage of blood–brain barrier...

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Detalles Bibliográficos
Autores principales: Wang, Xueting, Chen, Guijuan, Wan, Baolan, Dong, Zhangji, Xue, Yan, Luo, Qianqian, Wang, Dan, Lu, Yapeng, Zhu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486928/
https://www.ncbi.nlm.nih.gov/pubmed/35704676
http://dx.doi.org/10.1093/jmcb/mjac036