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Divergent Evolution of Lanthipeptide Stereochemistry

[Image: see text] The three-dimensional structure of natural products is critical for their biological activities and, as such, enzymes have evolved that specifically generate active stereoisomers. Lanthipeptides are post-translationally modified peptidic natural products that contain macrocyclic th...

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Detalles Bibliográficos
Autores principales: Sarksian, Raymond, van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486935/
https://www.ncbi.nlm.nih.gov/pubmed/36001880
http://dx.doi.org/10.1021/acschembio.2c00492