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Divergent Evolution of Lanthipeptide Stereochemistry
[Image: see text] The three-dimensional structure of natural products is critical for their biological activities and, as such, enzymes have evolved that specifically generate active stereoisomers. Lanthipeptides are post-translationally modified peptidic natural products that contain macrocyclic th...
Autores principales: | Sarksian, Raymond, van der Donk, Wilfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486935/ https://www.ncbi.nlm.nih.gov/pubmed/36001880 http://dx.doi.org/10.1021/acschembio.2c00492 |
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