A One-Pot Synthesis-Functionalization Strategy for Streamlined Access to 2,5-Disubstituted 1,3,4-Oxadiazoles from Carboxylic Acids

[Image: see text] A one-pot 1,3,4-oxadiazole synthesis-arylation strategy for accessing 2,5-disubstituted 1,3,4-oxadiazoles, from carboxylic acids, N-isocyaniminotriphenylphosphorane (NIITP), and aryl iodides, is reported. The reaction sequence, featuring a second stage copper-catalyzed 1,3,4-oxadia...

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Detalles Bibliográficos
Autores principales: Matheau-Raven, Daniel, Dixon, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486941/
https://www.ncbi.nlm.nih.gov/pubmed/36054913
http://dx.doi.org/10.1021/acs.joc.2c01669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486941/
https://www.ncbi.nlm.nih.gov/pubmed/36054913
http://dx.doi.org/10.1021/acs.joc.2c01669

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