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Reduction of Substituted Benzo-Fused Cyclic Sulfonamides with Mg-MeOH: An Experimental and Computational Study

[Image: see text] A study involving the use of Mg-MeOH for the double reductive cleavage of both N–S and C–S bonds in a series of 11 benzo-fused cyclic sulfonamides is reported. Examples where the sulfonamide nitrogen atom is part of a pyrrolidine ring effectively undergo reduction, as long as a met...

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Detalles Bibliográficos
Autores principales: Khalifa, Aisha, Redmond, Robert, Sánchez-Sanz, Goar, Evans, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486945/
https://www.ncbi.nlm.nih.gov/pubmed/36049485
http://dx.doi.org/10.1021/acs.joc.2c01169