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Bis-Thiourea Chiral Sensor for the NMR Enantiodiscrimination of N-Acetyl and N-Trifluoroacetyl Amino Acid Derivatives

[Image: see text] A C2-symmetrical bis-thiourea chiral solvating agent (CSA), TFTDA, for NMR spectroscopy has been obtained by reacting (1R,2R)-1,2-bis(2-hydroxyphenyl)ethylenediamine and 3,5-bis(trifluoromethyl)phenyl isothiocyanate. TFTDA shows remarkable propensity to enantiodiscriminate N-triflu...

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Detalles Bibliográficos
Autores principales: Recchimurzo, Alessandra, Balzano, Federica, Uccello Barretta, Gloria, Gherardi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486950/
https://www.ncbi.nlm.nih.gov/pubmed/36062357
http://dx.doi.org/10.1021/acs.joc.2c00814