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Initial activation of STAT2 induced by IAV infection is critical for innate antiviral immunity

STAT2 is an important transcription factor activated by interferons (IFNs) upon viral infection and plays a key role in antiviral responses. Interestingly, here we found that phosphorylation of STAT2 could be induced by several viruses at early infection stage, including influenza A virus (IAV), and...

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Detalles Bibliográficos
Autores principales: Li, Xinxin, Liu, Siya, Rai, Kul Raj, Zhou, Wenzhuo, Wang, Song, Chi, Xiaojuan, Guo, Guijie, Chen, Ji-Long, Liu, Shasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486978/
https://www.ncbi.nlm.nih.gov/pubmed/36148221
http://dx.doi.org/10.3389/fimmu.2022.960544