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Quality by design approach for development and validation of a RP-HPLC method for simultaneous estimation of xipamide and valsartan in human plasma

A new rapid, simple, and sensitive RP-HPLC method was carried out through applying Quality by Design approach for determination of xipamide and valsartan in Human plasma. Fractional factorial design was used for screening of four independent factors: pH, flow rate, detection wavelength, and % of MeO...

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Detalles Bibliográficos
Autores principales: Sebaiy, Mahmoud M., El-Adl, Sobhy M., Baraka, Mohamed M., Hassan, Amira A., El-Sayed, Heba M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487044/
https://www.ncbi.nlm.nih.gov/pubmed/36127740
http://dx.doi.org/10.1186/s13065-022-00864-4