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ANGPTL3 is involved in kidney injury in high-fat diet-fed mice by suppressing ACTN4 expression

OBJECTIVE: We wanted to explore how angiopoietin-like 3 (ANGPTL3) impact hyperlipidemia-induced renal injury. METHODS: ANGPTL3 knockout mice and wild-type C57 mice were set up in four groups (N = 5) depending on a normal or 60% high-fat diet: wild-type with normal diet (WT), angptl3-/- with normal d...

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Detalles Bibliográficos
Autores principales: Li, Guanyu, Lu, Di, Wang, Jingzhi, Yue, Shuling, Tan, Mei, Liu, Ming, Gao, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487085/
https://www.ncbi.nlm.nih.gov/pubmed/36123608
http://dx.doi.org/10.1186/s12944-022-01700-3