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Translation of a tissue epigenetic signature to circulating free DNA suggests BCAT1 as a potential noninvasive diagnostic biomarker for lung cancer

Lung cancer patients are diagnosed at late stages when curative treatments are no longer possible; thus, molecular biomarkers for noninvasive detection are urgently needed. In this sense, we previously identified and validated an epigenetic 4-gene signature that yielded a high diagnostic performance...

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Detalles Bibliográficos
Autores principales: Palanca-Ballester, Cora, Hervas, David, Villalba, Maria, Valdes-Sanchez, Teresa, Garcia, Diana, Alcoriza-Balaguer, Maria Isabel, Benet, Marta, Martinez-Tomas, Raquel, Briones-Gomez, Andres, Galbis-Caravajal, Jose, Calvo, Alfonso, Juan, Oscar, Lahoz, Agustin, Cases, Enrique, Sandoval, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487112/
https://www.ncbi.nlm.nih.gov/pubmed/36123616
http://dx.doi.org/10.1186/s13148-022-01334-3